Can AI Predict the Quantum Universe?

Zigzagging through time

During the spring of 2022, I felt as though I kept dashing backward and forward in time. At the beginning of the season, hay fever plagued me in Maryland. Then, I left to present talks in southern California. There — closer to the equator — rose season had peaked, and wisteria petals covered the ground near Caltech’s physics building.

From California, I flew to Canada to present a colloquium. Time rewound as I traveled northward; allergies struck again. After I returned to Maryland, the spring ripened almost into summer. But the calendar backtracked when I flew to Sweden: tulips and lilacs surrounded me again.

Quantum information processing

The zigzagging through horticultural time disoriented my nose, but I couldn’t complain: it echoed the quantum information processing that collaborators and I would propose that summer. We showed how to improve quantum metrology — our ability to measure things, using quantum detectors — by simulating closed timelike curves.

Closed timelike curves

A closed timelike curve is a trajectory that loops back on itself in spacetime. If on such a trajectory, you’ll advance forward in time, reverse chronological direction to advance backward, and then reverse again.

Author Jasper Fforde illustrates closed timelike curves in his novel The Eyre Affair. A character named Colonel Next buys an edition of Shakespeare’s works, travels to the Elizabethan era, bestows them on a Brit called Will, and then returns to his family. Will copies out the plays and stages them. His colleagues publish the plays after his death, and other editions ensue. Centuries later, Colonel Next purchases one of those editions to take to the Elizabethan era.

Closed timelike curves can exist according to Einstein’s general theory of relativity. But do they exist? Nobody knows. Many physicists expect not. But a quantum system can simulate a closed timelike curve, undergoing a process modeled by the same mathematics.

Quantum systems and correlations

Two entities share correlations if a change in one entity tracks a change in the other. Two classical systems can correlate; for example, your brain is correlated with mine, now that you’ve read writing I’ve produced. Quantum systems can correlate more strongly than classical systems can, as by entangling.

Suppose Colonel Next correlates two nuclei and gives one to his daughter before embarking on his closed timelike curve. Once he completes the loop, what relationship does Colonel Next’s nucleus share with his daughter’s? The nuclei retain the correlations they shared before Colonel Next entered the loop, according to Seth and collaborators. When referring to closed timelike curves from now on, I’ll mean ones of Seth’s sort.

Quantum metrology

How can we apply closed timelike curves in quantum metrology? In Fforde’s books, Colonel Next has a brother, named Mycroft, who’s an inventor. Suppose that Mycroft is studying how two particles interact (e.g., by an electric force). He wants to measure the interaction’s strength. Mycroft should prepare one particle — a sensor — and expose it to the second particle. He should wait for some time, then measure how much the interaction has altered the sensor’s configuration. The degree of alteration implies the interaction’s strength. The particles can be quantum, if Mycroft lives not merely in Sherlock Holmes’s world, but in a quantum-steampunk one.

But how should Mycroft prepare the sensor — in which quantum state? Certain initial states will enable the sensor to acquire ample information about the interaction; and others, no information. Mycroft can’t know which preparation will work best: the optimal preparation depends on the interaction, which he hasn’t measured yet.

Quantum teleportation

Mycroft can overcome this dilemma via a strategy published by my collaborator David Arvidsson-Shukur, his recent student Aidan McConnell, and me. According to our protocol, Mycroft entangles the sensor with a third particle. He subjects the sensor to the interaction (coupling the sensor to particle #2) and measures the sensor.

Then, Mycroft learns about the interaction — learns which state he should have prepared the sensor in earlier. He effectively teleports this state backward in time to the beginning-of-protocol sensor, using particle #3 (which began entangled with the sensor). Quantum teleportation is a decades-old information-processing task that relies on entanglement manipulation. The protocol can transmit quantum states over arbitrary distances — or, effectively, across time.

AI and quantum phenomena

AI promises to revolutionize the way we do science, which raises a central technological question of our time: Can classical AI understand all natural phenomena, or are some fundamentally beyond its reach? Many proponents of artificial intelligence argue that any pattern that can be generated or found in nature can be efficiently discovered and modeled by a classical learning algorithm, implying that AI is a universal and sufficient tool for science.

The word “classical” is important here to contrast with quantum computation. Nature is quantum mechanical, and the insights of Shor’s algorithm [1] along with quantum error correction [2,3,4] teach us that there are quantum systems, at least ones that have been heavily engineered, that can have trajectories that are fundamentally unpredictable by any classical algorithm, including AI. This opens the possibility that there are complex quantum phenomena occurring naturally in our universe where classical AI is insufficient, and we need a quantum computer in order to model them.

Quantum sampling

In 2019 Google demonstrated quantum supremacy on a digital quantum device [5], and in 2024 their latest chip performed a task in minutes where our best classical computers would take 10^25 years [6]. The task they performed is to prepare a highly entangled many-body quantum state and to sample from the corresponding distribution over classical configurations. Quantum supremacy on such sampling problems is on firm ground, with results in complexity theory backing up the experimental claims [7].

However, quantum sampling alone does not refute the universality of classical AI. The output of quantum sampling often appears completely featureless, which cannot be verified by any classical or quantum algorithm, or by any process in our universe for that matter. For example, running the exact same sampling task a second time will produce a list of configurations that will appear unrelated to the original. In order for a phenomenon to be subject to scientific prediction, there must be an experiment that can confirm or deny the prediction. So if quantum sampling has no features that can be experimentally verified, there is nothing to predict, and no pattern for the AI to discover and model.

Quantum chemistry and condensed matter physics

There are many unsolved problems in quantum chemistry and condensed matter physics that are inaccessible using our best classical simulation algorithms and supercomputers. For example, these occur in the strongly correlated regime of electronic structure in quantum chemistry, and around low-temperature phase transitions of condensed matter systems. We do not understand the electronic structure of FeMoco, the molecule responsible for nitrogen fixation in the nitrogenase enzyme, nor do we understand the phase diagram of the 2D Fermi-Hubbard lattice and whether or not it exhibits superconductivity.

It is possible there are no fundamental barriers for a sufficiently advanced AI to solve these problems. Researchers in the field have achieved major breakthroughs using neural networks to predict complex biological structures like protein folding. One could imagine similar specialized AI models that predict the electronic structure of molecules, or that predict quantum phases of matter. Perhaps the main reason it is currently out of reach is a lack of sufficient training data. Here lies a compelling opportunity for quantum computing: The only feasible way to generate an abundance of accurate training data may be to use a quantum computer, since physical experiments are too difficult, too unreliable, and too slow.

Truly complex quantum signals

While AI might be able to learn much of the patterns of physics and chemistry from quantum-generated data, there remains a deeper possibility: The quantum universe may produce patterns that AI cannot compress and understand. If there are quantum systems that display signals that are truly classically complex, then predicting the pattern will require a quantum computer at inference time, not only in training.

We’ll now envision how such a signal could arise. Imagine a family of quantum systems of arbitrary size N, and at each size N there is a number of independent parameters that is polynomial in N, for example the coefficients of a Hamiltonian or the rotation angles of a quantum circuit. Suppose the system has some physical feature whose signal we would like to compute as a function of the parameters, and this signal has the following properties:

1. (Signal) There is a quantum algorithm that efficiently computes the signal. For example, the signal cannot be exponentially small in N.
2. (Verifiable) The signal is verifiable, at least by an ideal quantum computer. For example, the task could be to compute an expectation value.
3. (Typically complex) When the parameters are chosen randomly, the signal is computationally hard to classically compute in the average case.

If these properties hold, then it’s possible that no machine learning model using a polynomial amount of classical compute can perform the task, even with the help of training data.

The requirement of verifiability by a quantum process ensures that the signal being computed is a robust phenomenon where there is some “fact of the matter”, and a prediction can be confirmed or denied by nature. For example, this holds for any task where the output is the expectation value of some observable. The average-case hardness ensures that hard instances really exist and can be easily generated, rather than only existing in some abstract worst-case that cannot be instantiated.

There is a connection between the verifiability of a computation and its utility to us. Suppose we use a computer to help us design a high-temperature superconductor. If our designed material indeed works as a high-temperature superconductor when fabricated, this forms a verification of the predictions made by our computer. Utility implies verifiability, and likewise, unverifiable computations cannot be useful. However, since nature is quantum, a computation need not be classically verifiable in order to be useful, but only quantumly verifiable.

Making progress

John Preskill’s “entanglement frontier” seeks to understand the collective behavior of many interacting quantum particles [10]. In order to shed light on the fundamental limits of classical AI and the utility of quantum computers in this regime, we must understand if the exponential Hilbert space of quantum theory remains mostly hidden, or if it reveals itself in observable phenomena. The search for classically complex signals forms an exciting research program for making progress. Google recently performed the first demonstration of a classically complex signal on a quantum device: The out-of-time-order correlators3 of random quantum circuits [9]. We can seek to find more such examples, first in abstract models, and then in the real world, to understand how abundant they are in nature.

References

[1] Shor, Peter W. “Algorithms for quantum computation: discrete logarithms and factoring.” Proceedings 35th annual symposium on foundations of computer science. Ieee, 1994.
[2] Shor, Peter W. “Scheme for reducing decoherence in quantum computer memory.” Physical review A 52.4 (1995): R2493.
[3] Shor, Peter W. “Fault-tolerant quantum computation.” Proceedings of 37th conference on foundations of computer science. IEEE, 1996.
[4] Kitaev, A. Yu. “Fault-tolerant quantum computation by anyons.” Annals of physics 303.1 (2003): 2-30.
[5] Arute, Frank, et al. “Quantum supremacy using a programmable superconducting processor.” Nature 574.7779 (2019): 505-510.
[6] Morvan, Alexis, et al. “Phase transitions in random circuit sampling.” Nature 634.8033 (2024): 328-333.
[7] Aaronson, Scott, and Alex Arkhipov. “The computational complexity of linear optics.” Proceedings of the forty-third annual ACM symposium on Theory of computing. 2011.
[8] Huang, Hsin-Yuan, et al. “Provably efficient machine learning for quantum many-body problems.” Science 377.6613 (2022): eabk3333.
[9] Abanin, Dmitry A., et al. “Constructive interference at the edge of quantum ergodic dynamics.” arXiv preprint arXiv:2506.10191 (2025).
[10] Preskill, John. “Quantum computing and the entanglement frontier.” arXiv preprint arXiv:1203.5813 (2012).

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